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2025
163. Jiang W.; Hou, Q.; Hua, D.; Zeng, Y.; Huang, C.; Luo, G.; Li, K.; Jin, Z.; Chen, X.; Li, W.; Chu, Q.; Jiang, Z.; Wu, X. Discovery of Potent and Orally bioavailable BenzoazepinamineBased SHP2 Allosteric Inhibitors for the Treatment of Inflammatory Diseases. J. Med. Chem. 2025, 68, 22599-22618.
162. Bai, X.,# Yao, J.,# Zhang, M., Peng, Q., Li, W., Yin, Y., and Jiang, Z.,* Kinetic Resolution for 1,4-Spin-Center Shift-Based Reduction of Azaarene-Functionalized Secondary and Tertiary Allylic Alcohols. J. Am. Chem. Soc. 2025, DOI: 10.1021/jacs.5c15917. https://doi.org/10.1021/jacs.5c15917
161. Shao, T., Li, Z., Nie, F., Li, Q., Zhao, X., and Jiang, Z.,* Leveraging electron donor–acceptor complexes for kinetic resolution in catalytic asymmetric photochemical synthesis. Nat. Chem. 2025, 17, 1722–1731. DOI:10.1038/s41557-025-01973-y. https://doi.org/10.1038/s41557-025-01973-y
160. Huo, J., Yang, S., Kong, M., Xi, M., Qiao, B.,* and Jiang, Z.,* Photoredox catalytic asymmetric dearomative [3+2] cycloaddition of isoquinolines with enones. Nat. Commun. 2025, DOI: 10.1038/s41467-025-62876-7. https://doi.org/10.1038/s41467-025-62876-7
159. Dai,Y., Huang,Y., Wang,Y., Lin,Y., Liu,Y., Wei,Q., Zhao,X., Yin,Y.,* and Jiang,Z.,* Photocatalytic Asymmetric Oxidation of Phosphines with Water. J. Am. Chem. Soc. 2025, DOI:10.1021/jacs.5c11656.
https://doi.org/10.1021/jacs.5c11656
158. Lin, Y., Sun, X., Dai, Y., Liu, S., Yin, Y.,* and Jiang, Z.,* Photochemical Synthesis of α‑Substituted Vinylazaarenes Enabled by Thia-PaternÒ-BÜchi Reactions. Org. Lett. 2025, DOI:10.1021/acs.orglett.5c02390.
https://doi.org/10.1021/acs.orglett.5c02390
157. Zeng,G., Shi,W., Wang,Z., Zhao,X., Yin,Y.,* and Jiang,Z.,* Triplet Energy Transfer-Based Deracemization of Axially Chiral Alkenes Enabled by a Dual catalyst system. J. Am. Chem. Soc. 2025, DOI:10.1021/jacs.5c10123.
https://doi.org/10.1021/jacs.5c10123
156. Han,C.,# Wang, L.,# Zhao, X., Qiao, B.,* and Jiang,Z.,* Photocycloaddition of quinolines and cyclopropanes via electron donor-acceptor relay energy transfer strategy. Sci. China Chem. 2025, 68, DOI:10.1007/s11426-025-2650-x.https://doi.org/10.1007/s11426-025-2650-x
155. Cao,S.,* Meng,Y., Guo,J., Chen,J., and Jiang,Z.,* In-Depth Insights into the Enantioselective Ketyl-Olefin Cyclizations Promoted by Reductive Multisite Proton-Coupled Electron Transfer. ACS Catal. 2025,15, 11852-11860. DOI: 10.1021/acscatal.5c02740. http://doi.org/10.1021/acscatal.5c02740
154. Liu, F.; Guo, Y.; Lu, W.; Zhao; X. Yin, Y.; and Jiang, Z. Precise Construction of Spiro Stereocenters via Enantioselective Radical Addition through Modulating Photocatalysis from Redox to Energy Transfer. Chem. Sci. 2025, 16, 10555-10562.
153. Li, Q.; Zhao, X.; Yin, Y.; Shao, T.; and Jiang, Z. Asymmetric Photoredox Catalytic Minisci-Type Reactions of α‑Bromide Amides. Org. Lett. 2025, 27, 1244-1249.
152. Tian, D.; Pan, X.; Yin, Y.; and Jiang, Z. Chiral Lewis Acid-Catalyzed Intramolecular [2 + 2] Photocycloaddition: Enantioselective Synthesis of AzaareneFunctionalized Azabicyclo[2.1.1]hexanes and Bicyclo[1.1.1]pentanes. J. Am. Chem. Soc. 2025, 147, 12410-12417.
151. Shao, T.; Nie, F.; Cao, S.; Li, Q.; Zhao, X.; Yin, Y.; Jiang, Z. Kinetic Resolution of Racemic Radicals in Asymmetric Photoredox Minisci Reactions with Azaarenes for Precise Construction of Two Non-adjacent Stereocenters. J. Am. Chem. Soc. 2025, 147, 10002-10011.
150. Jiang, C.; Meng, Y.; Huang, Y.; Liu, C.; Yin, Y.; Zhao, X.; Cao, S.; and Jiang, Z. Chiral Primary Amine-Catalyzed Asymmetric Photochemical Reactions of Pyridotriazoles with Boronic Acids to Access Triarylmethanes. J. Am. Chem. Soc. 2025, 147, 5320-5329.
149. Sun, X.; Zhu, W.; Yin, Y.; Zhao, X.; and Jiang, Z. From Radical Coupling to Enantioselective Controlled Protonation: Advancing Precise Construction of Stereocenters. J. Am. Chem. Soc. 2025, 147, 4382-4392.
148. Jiang, C.; Yin, Y.; Jiang, Z. Advances in Photoenzyme-Catalyzed Asymmetric Radical Addition Reactions. Chin. J. Org. Chem. 2025, 45, 1614-1633.
147. Jiang, C.; Yin, Y.; Jiang, Z. Advances in Photoenzyme-Catalyzed Asymmetric Radical Addition Reactions. Chem. Soc. Rev. 2025, 54, 2246-2274.
146. Yin, Y.; You, M.; Li, X.; Jiang, Z. Catalytic asymmetric photocycloaddition reactions mediated by enantioselective radical approaches. Chem. Sci. 2025, 16, 5957-5966.
145. Liu, Y.; Wang, J.; Yin, Y.; Jiang, Z. Recent Advances in Catalytic Atroposelective Synthesis of Axially Chiral Quinazolinones. Catalysts 2025, 15, 426-447.
144. Zhang, Y.; Guo, Z.; Qiu, R.; Ren, Z.; Huo, J.; Yang, Y.; Qiao, B.; Jiang, Z.; and Liu, T. Liu, Y.; Wang, J.; Yin, Y.; Jiang, Z. The ConPET Mechanism Remains Veiled: Reply to “Unlocking the ConPeT Mechanism”. Angew. Chem. Int. Ed. 2025, 64, e202514007.
